Children:
- Isaac Huff died INFANT.
- Jenny "Jane" Huff was born 21 Jul 1784, Virginia; died 27 Mar 1865, Cocke County; was buried Estill Stokely Cemetery, Cocke County, Tennessee.
- Mary Elizabeth Huff
- Nellie Huff
- Catherine "Katie" Huff was born 4 Feb 1805; died 1826; was buried Huff Cemetery, Cocke County, Tennessee.
- Leonard Huff
- 2. Thomas B. Huff was born 17 May 1808; died 24 Nov 1858; was buried Huff-Susong Cemetery, Cocke County, Tennessee.
- Stephen Huff was born 12 Jul 1796, Tennessee; died 17 Mar 1870; was buried Stephen Huff Cemetery, Cocke County, Tennessee.
- David Huff
- Peter Huff
- John Huff
- Nathan Huff
- Joseph Huff was born 26 Mar 1794; died 23 Aug 1846; was buried Huff-Susong Cemetery, Cocke County, Tennessee.
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